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          Pharmaceutical intermediates

          Anti-tumor drugs

          Name

          Key intermediate

          CAS NO
          Axitinib

          3,6-diiodo(1H)indazole

          Methyl 2-mercaptobenzoate

          319472-78-1

          4892-02-8

          Crizotinib

          4-Iodo-1H-pyrazole

          (R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-2-nitropyridine

          4-(4-Bromopyrazol-1-yl)piperidine-1-carboxylic acid tert-butyl ester

          (R)-5-bromo-3-(1-

          3469-69-0

          877397-70-1

          877399-50-3

          877399-00-3

          Lapatinib

          2-(Methylsulfonyl)-ethanamine hydrochloride

          N-[3-Chloro-4-(3-fluorobenzyloxy)phenyl]-6-iodoquinazolin-4-amine

          3-Chloro-4-(3-fluorobenzyloxy)aniline

          104458-24-4

          231278-20-9

          202197-26-0

          Pazopanib

          3-Methyl-6-nitro-1H-Indazole

          2,3-dimethyl-6-nitro-2H-indazole

          2,3-dimethyl-2H-indazol-6-amine

          2,4-Dichloropyrimidine

          3-Amino-6-methylbenzenesulfonam

          6494-19-5

          444731-73-1

          444731-72-0

          3934-20-1

          6973-09-7

          Regorafenib

          3-Fluoro-4-Nitrophenol

          3-Fluoro-4-aminophenol

          394-41-2

          399-95-1

          Afatinib

          trans 4-Dimethylaminocrotonic acid hydrochloride

          848133-35-7

          Gefitinib

          4-(3-chloropropyl)-morpholin

          7357-67-7

          Anti-inflammatory drugs

          Name

          Key intermediate

          CAS NO
          Tofacitinib

          1-benzyl-4-methylpiperidin-3-ol 4-methylbenzenesulfonate

          (3R,4R)-1-benzyl-N,4-dimethylpiperidin-3-amine hydrochloride

          2,4-Dichloro-1H-pyrrolo[2,3-d]pyrimidine

          3-bis(4-

          493040-20-3

          477600-70-7

          90213-66-4

          477600-71-8

          Formoterol

          2-Bromo-4'-Benzyloxy-3'-nitroacetophenone

          (1R,2S)-1-Amino-2-indanol

          43229-01-2

          136030-00-7

          Umeclidiniu

          Phenyl(piperidin-4-yl)methanone

          37586-22-4

          Hypoglycemic agents

          Name

          Key intermediate

          CAS NO
          Alogliptin

          (R)-3-Boc-aminopiperidine

          309956-78-3

          Anagliptin

          2-Methylpyrazolo[1,5-a]pyriMidine-6-carboxylic acid

          2-Methylpyrazolo[1,5-a]pyrimidine-6-carboxamide

          1,2-Diamino-2-methylpropane

          739364-95-5

          338953-49-4

          811-93-8

          Dapagliflozin

          5-Bromo-2-chloro-4’-ethoxydiphenylmethane

          4-Iodo-1-chloro-2-(4-ethoxybenzyl)benzene

          (5-bromo-2-chlorophenyl)(4-ethoxyphenyl)methanone

          461432-23-5

          1103738-29-9

          461432-22-4

          Vildagliptin

          3-Amino-1-adamantanol

          (2S)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile

          L-Prolinamide

          702-82-9

          207557-35-5

          7531-52-4

          Canagliflozin

          2-(4-fluorophenyl)thiophene

          (5-(4-fluorophenyl)thiophen-2-yl)(5-iodo-2-methylphenyl)methanone

          2-(4-fluorophenyl)-5-(5-iodo-2-methylbenzyl)thiophene

          (5-bromo-2-methylph

          58861-48-6

          1071929-08-2

          898566-17-1

          1132832-75-7

          1030825-20-7

          Anticoagulants drugs

          Name

          Key intermediate

          CAS NO
          Dabigatran

          N-(4-Cyanophenyl)glycine

          4-(Methylamino)-3-nitrobenzoic Acid

          3-(Pyridin-2-ylamino)propanoate

          Ethyl N-[3-amino-4-(methylamino)benzoyl]-N-pyridin-2-yl-beta-alaninate

          42288-26-6

          41263-74-5

          103041-38-9

          212322-56-0

          Ticagrelor

          4,6-dichloro-5-nitro-2-(propylsulfanyl)pyrimidine

          (1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine

          (1R,2R)-2-(3,4-difluorophenyl) cyclopropanamine(S)-(carboxylato(phenyl) methyl)h

          145783-14-8

          220352-38-5

          376608-71-8

          Antiepileptics drugs

          Name

          Key intermediate

          CAS NO
          Retigabine (ezogabine)

          2-Amino-5-[(4-fluorobenzyl)amino]-1-nitrobenzene

          4-(4-Fluorobenzylamino)-1,2-phenylenediamine

          150812-21-8

          491871-67-1

          Anti-HIV drugs

          Name

          Key intermediate

          CAS NO
          Abacavir

          (2-Amino-4,6-dichloro-5-pyrimidinyl)formamide

          (1S,4R)-4-(2-amino-6-chloro-9H-purin-9-yl)-2-Cyclopentene-1- methano

          171887-03-9

          136522-33-3

          Etravirine

          (4-Cyanophenyl)guanidine

          4-Aminobenzonitrile

          5637-42-3

          873-74-5

          Ritonavir

          154212-59-6

          154212-61-0

          144164-11-4

          154212-59-6

          154212-61-0

          144164-11-4

          Atazanavir

          4-(2-Pyridinyl)- benzaldehyde

          N-(Methoxycarbonyl)-L-tert-leucine

          Tert-Butyl[(1S)-1-(2R)-Oxiranyl-2-Phenylethyl]carbamate

          2-[[4-(2-Pyridinyl)phenyl]methylene]- hydrazin

          127406-56-8

          162537-11-3

          98760-08-8

          198904-84-6

          198904-86-8

          Aliskiren

          5-Bromo 2-methoxy phenol

          37942-01-1

          Antihypertensives drugs

          Name

          Key intermediate

          CAS NO
          Aliskiren

          5-Bromo 2-methoxy phenol

          37942-01-1

          Custom Products

          Code

          Name

          CAS NO

          112 Chloro [1,1-biphenyl] 2,5-diol

          117-71-5

          113 3-amino-2-methoxy-dibenzofuran

          5834-17-3

          120 2-methoxy - dibenzofuran 20357-70-4
          394 2- hydroxydibenzofuran 86-77-1
          396 3-nitro-2-methoxy-dibenzofuran 2672-81-3
          392 3-hydroxy -N- (2- methoxy-3-dibenzofuran-yl) -2-naphthalene-carboxamide 96460-88-7
          810 3-phenoxy-propionic acid ethyl ester 22409-91-2
          368 Heptachloropropane 3849-33-0
          246 Dibenzyl diphosphite of tetraethyl 4546-4-7
          372 2-nitropropane 79-46-9
          373 2,3-dimethyl-2,3-dinitro-butane 3964-18-9
          202 4,4-diiodo-biphenyl 3001-15-8
          1016 2,4 Nitrodiphenylamine

          961-68-2

          1024 Cinnamic acid isopropyl ester 3001-15-8
          325 Dichloro glyoxime 2038-44-0
          1037 Acetoacetate (2-methoxy) ethyl 22502-03-0
          1074 D-3-bromo-camphor-8-sulfonic acid ammonium salt 22502-03-0
          111 Arecoline hydrobromide hydrochloride 300-08-3
          201 4- iodobiphenyl 1591-31-7
          375 2-methyl-4,6-dichloro-5-aminopyrimidine 39906-04-2
          601 Diethyl oxaloacetate sodium salt 40876-98-0
          990 O Nitrodiphenylamine 119-75-5
          925 Azomethine -H- monosodium salt monohydrate 206752-32-1
          1035 4-hydroxyisophthalic acid 636-46-4
          6-Chloro-indol-2-one 56341-37-8
          2- -aminoindan 2975-41-9
          1- Bromocarbazole 16807-11-7
          N- methyl trifluoroacetamide 815-06-5
          2,8-dibromo dibenzofuran 10016-52-1
          2-bromo-1- (2,2-dimethyl -4H-1,3- benzodioxin-6-yl) ethanone 102293-80-1
          N, N- diethyl ethyl acrylate 13894-28-5
          3'-nitro-4'-benzyloxy-2-bromoacetophenone 43229-01-2
          600 6-hydroxy-1-naphthoic acid 2437-17-4
          Between 4-methoxy-phthalate 2206-43-1
          2-nitropropane 79-46-9
          D-3-bromo-camphor-8-sulfonic acid ammonium salt D-3-bromo-camphor-8-sulfonic acid ammonium salt
          dioctyl 3,4,5,6-tetrabromophthalate

          26040-751-7

          Benzonitrile, 3-ethoxy-4-methoxy-

          60758-86-3

          1-Bromo-3-ethoxy-4-methoxybenzene

          52849-52-2

          4-Bromoveratrole

          2859-78-1

          Cyclen

          294-90-6

          Amisulpride

          71675-85-9

          Valproic acid

          99-66-1

          Cyclobutanecarboxylic acid

          3721-95-7

          DL-Mandelic acid

          90-64-2;611-72-3

          45 Records
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